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Protein synthesis

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Genes are recipes for proteins. Protein synthesis turns the DNA code into a working protein. Separate Biology, Higher.

The genetic code

Three bases (a triplet, or codon) code for one amino acid.
The order of bases in a gene decides the order of amino acids, which decides the protein's shape and function.

Transcription

Happens in the nucleus. The DNA unzips and a copy of one gene is made as mRNA (messenger RNA).
mRNA is small enough to leave the nucleus.

Translation

Happens at a ribosome in the cytoplasm. The ribosome reads the mRNA three bases at a time.
tRNA molecules bring the matching amino acids, which are joined into a chain. The chain folds into a protein.
Worked example

A gene is 300 bases long. How many amino acids does it code for?

  1. Three bases code for one amino acid.
  2. 300 ÷ 3

Answer: 100

Key idea

A triplet of bases codes for one amino acid. Transcription copies a gene into mRNA in the nucleus. Translation at a ribosome uses tRNA to join amino acids into a protein.

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